Medium power: Pap stain
Clusters of pancreatic acinar cells (lower right) and flat sheets of benign ductal epithelial cells (upper left)
High power: Pap stain
Flat cohesive 2D sheet of benign ductal epithelial cells with round uniform nuclei (honeycomb-like architecture). Note columnar morphology of cells at the edge.
Features
Architecture
• 2D flat cohesive sheets (honeycomb)
Cellular features
• Small uniform orderly cells
• Moderate delicate cytoplasm
• Cytoplasm may have mucin vacuoles
Nuclear features
• Round uniform bland nuclei
• Even fine chromatin
• Small inconspicuous nucleoli
Background
• May have contaminating gastrointestinal cells