Pap stain, low power
High cellularity and predominantly cohesive flat sheets of cells
Pap stain, high power
The large sheet of cells with finely vacuolated cytoplasm, slightly enlarged oval nuclei with no nuclear size variation
Features
• Directed washing in cases of upper tract malignancy
• High cellularity
• Predominantly cohesive groups
• Flat sheets of cells
• Homogenous cytoplasm
• Slightly increased nucleus to cytoplasmic ratio
• Enlarged nuclei
• Central nuclear location
• Minimal nuclear size variation
• Round to oval nuclei
• Minimal nuclear membrane irregularity
• No nuclear membrane thickening
• Fine chromatin
• Small, indistinct nucleoli may be seen
• Presumed benign pelvic wash on one side may serve as a baseline for evaluating whether atypia on contralateral side is due to malignancy or not.