Low power: Pap stain
Small clusters of pancreatic acinar cells
Medium power: Pap stain
Clusters of pancreatic acinar cells (lower right) and flat sheets of benign ductal epithelial cells (upper left)
High power: Pap stain
Pancreatic acinar cells with round uniform nuclei and abundant granular cytoplasm
Features
Architecture
• Grape like clusters
Cellular features
• Small polygonal cells
• Abundant granular cytoplasm
• Cytoplasm may be vacuolated following degranulation
Nuclear features
• Round uniform eccentrically located nuclei
• Even granular chromatin
• Prominent nucleoli
Background
• May have contaminating gastrointestinal cells