Low power: DQ stain
Triad of epithelial cells, scattered mesenchymal/myoepithelial cells and metachromatic stroma
Medium power: DQ stain
Triad of epithelial cells, scattered mesenchymal/myoepithelial cells and metachromatic stroma
High power: DQ stain
Epithelial cells embedded in stroma. Cells are small round and uniform with delicate cytoplasm
Low power: Pap stain
Triad of epithelial cells, scattered mesenchymal/myoepithelial cells and metachromatic stroma
Medium power: Pap stain
Triad of epithelial cells, scattered mesenchymal/myoepithelial cells and metachromatic stroma
High power: DQ stain
Epithelial cells embedded in stroma. Cells are small round and uniform with fine chromatin, small nucleoli and delicate cytoplasm
Medium power: Pap stain
Epithelial and myoepithelial cells embedded in stroma. Cells are small round and uniform with delicate cytoplasm
Low power: DQ stain
Cellular pleomorphic adenoma
Cellular smear with triad of epithelial cells, mesenchymal cells and stroma
High power: DQ stain
Cellular pleomorphic adenoma
Cellular smear with triad of epithelial cells, mesenchymal cells and stroma
Low power: Pap stain
Cellular pleomorphic adenoma
Cellular smear with triad of epithelial cells, mesenchymal cells and stroma
High power: Pap stain
Cellular pleomorphic adenoma
Epithelial and mesenchymal cells embedded in stroma
High power: Pap stain
Cellular pleomorphic adenoma
Epithelial and mesenchymal cells embedded in fibrillary stroma
Features
• Cellular smears
• Small basaloid cells
• Cribriform, rosettes, tubular clusters
• Basaloid cells with metachromatic hyaline material
• Small round to oval cells
• Round and uniform nuclei
• Small nucleoli
• Moderate amount of pale cytoplasm
• May have nuclear grooves and inclusions
• May have intracytoplasmic mucin vacuoles
• Usually spindled
• May be epithelioid/ plasmacytoid
• Typically singly dispersed
• Elongated nuclei
• Delicate ill-defined cytoplasm
• Typically embedded in stroma
• Fibrillary with feathery outlines
• Is best seen on DQ stain as it appears magenta in color
• May have metaplasia: squamous, oncocytic, mucinous
• May have calcifications, crystals
• Express cytokeratin, vimentin, GFAP, may express CEA, actin, calponin, S100
• May have rearrangement of 8q12 or 12q13.15
Viguer JM et al. Acta Cytol. 1997 May-Jun;41(3):786-94.
Elsheikh TM et al. Acta Cytol. 1996 Nov-Dec;40(6):1165-75.
Domagala W et al. Acta Cytol. 1988 May-Jun;32(3):403-8.