Pap stain; High power
Predominantly superficial squamous cells, some of which are covered by coccobacilli (Clue cells)
Pap stain; Medium power
Clue cells
Pap stain; Medium power
Numerous superficial squamous cells covered with bacteria
Pap smears; High power
Clusters of coccobacilli in background. Some bacteria cover the squamous cells
Note that entire surface of the cell may not be covered to call it a clue cell
Features
Preparation type
• Liquid based
Architecture
• Dirty appearance of smear due to clumps of bacilli
• Less dirty in LBP than conventional
Cellular features
• Coccobacilli covering squamous cells
• Velvet-coat appearance
Background
• Lack of inflammation
• Absence of lactobacilli
Causative agent
• Gardnerella vaginalis (most common)